文件标题：Association of Parental Myopia With Higher Risk of Myopia Among Multiethnic Children Before School Age
Authors：徐娟江（1,2），克里斯蒂纳Tarcy-Hornoch（3,4），Susan A. Cotter（5），Saiko Matsumura（6），Paul Mitchell（7），Kathryn A. Rose（8），Joanne Katz（9），Seang-Mei Saw（6,10），Rohit Varma（11）
- USC Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of South California, Los Angeles
- 洛杉矶南加州大学凯克医学院预防医学系
- 大学眼科学系洗涤ton, Seattle
- Department of Ophthalmology, Seattle Children’s Hospital, Seattle, Washington
- 南加州验光学院，马歇尔B. Ketchum大学，富勒顿
- Singapore Eye Research Institute, Singapore
- Centre for Vision Research, Westmead Institute, Sydney, Australia
- 卫生大学卫生学院悉尼，澳大利亚Ultimo大学卫生学院纪律
- Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
- Saw Swee Hock School of Public Health, National University of Singapore, Singapore
- Southern California Eye Institute, CHA Hollywood Presbyterian Medical Centre, Los Angeles
Date:2020
参考：江X，Tarczy-Hornoch K，Cotter SA，Matsumura S，Mitchell P，Rose Ka，Katz J，Saw Sm，Varma R;POPEYE联盟。父母近视与学龄儿童前近视高近视风险的关联。贾马眼科莫尔。2020年5月1日; 138（5）：501-509。[链接到开放访问纸]
Summary
该队列研究了来自3名人口的9793名学前儿童的屈光和人口统计数据，探讨了父母近视和儿童近视发育的关联，特别是如果父母近视早盘。
父母的近视被定义为使用眼镜或隐形眼镜进行距离使用。发现近视父亲或母亲的儿童的近视患病率被认为是相似的（分别为13.3％和12.5％）。
父母的年龄成为近视是佛und to be significant, where myopic prevalence and myopic refractive error were increased for all of the children over 12 months old. Children with parents who first used distance spectacles when 11 years of age or younger had a myopia prevalence of 12.8% (from mother) or 13.4% (from father). When the myopia onset-age for the parents increased to between 12 and 20 years of age, the prevalence reduced to 10.9% for mothers and 12.1% for fathers. If the onset age was 21 years or older for both mother and father, the prevalence rate reduced further to approximately 8%.
对于具有近视父母的儿童，发现父母近视的效果是剂量依赖的，其中，近视父母的早期发病近视的可能性比例为1.42，对于父母双方的父母和3.39经历了早期发病的近视。
Myopia in parents was seen to be associated with an increased risk of myopia in pre-school children, a greater prevalence of myopia, a higher ratio of axial length to corneal curvature radius and a more myopic (or less hyperopic) refractive error, even for non-myopic children. This was found to be the case regardless of the race/ethnicity of the children featured in the studies.
P.arental myopia, especially childhood-onset, may provide a predisposition for young children developing myopia before starting school.
What does this mean for my practice?
在评估个人儿童发展近视的可能性时，Eyecare从业者可以深入进入父母的眼部历史并建立近视的年龄。如果它在12岁之前，这可能有助于突出有可能更早成为近视的儿童，因此将从早期的近视管理干预中受益。
What do we still need to learn?
Myopia in parents may influence myopia development in children by pre-disposing children to becoming myopic before school-age. However, further research could tell us the extent of the influence of parental myopia in myopia development, and if this varies across different ethnicities.
抽象的
标题：Association of Parental Myopia With Higher Risk of Myopia Among Multiethnic Children Before School Age
作者：Xuejuan Jiang，Kristina Tarcy-Hornoch，Susan A. Cotter，Saiko Matsumura，Paul Mitchell，Kathryn A. Rose，Joanne Katz，Seang-Mei Saw，Rohit Varma
P.urpose:To investigate the association of parental myopia with refractive error and ocular biometry in multiethnic children aged 6 to 72 months.
Methods:This cohort study pooled data from children in 3 population-based studies with comparable design from the US, Singapore, and Australia. Parental myopia was defined as the use of glasses or contact lenses for distance viewing by the child’s biological parent(s). Multivariable regressions were conducted to assess the association of parental myopia. Data were collected from 2003 to 2011 and analyzed from 2017 to 2019. Cycloplegic refraction and prevalence of myopia (spherical equivalent refractive error of≤−0.5 diopters [D]) in the more myopic eye.
Results:分析队列包括9793名儿童，其中包括4003个亚洲，2201名非洲裔美国人，1998西班牙裔美国人和1591名非西班牙裔美国人参与者（5106个男孩[52.1％];意思是[SD]年龄，40.0 [18.9]个月）。与没有父母近视的儿童相比，早期近视的差距为1.42（95％CI，1.20-1.68），儿童为近视，2.70（95％CI，2.19-333）为2名父母的儿童近视和3.39（95％CI，1.99-5.78），儿童有2名父母，童年发病近视。甚至在没有近视的儿童中，父母近视与轴向长度与角膜曲率半径的比例更大（父母在父母两者近视的回归系数，0.023;P. < .001) and more myopic refractive error (regression coefficient for myopia in both parents, −0.20 D;P. < .001). Effects of parental myopia were observed in all 4 racial/ethnic groups and across age groups except those younger than 1 year. However, parental myopia was not associated with the age-related trends of refractive error (regression coefficient for children without parental myopeia, 0.08; for children with 2 parents with myopia, 0.04;P. = .31 for interaction) and ratio of axial length to corneal curvature radius (regression coefficient for children without parental myopia, 0.031; for children with 2 parents with myopia, 0.032;P. = .89 for interaction) beyond infancy.
Conclusions:P.arental myopia, especially childhood-onset parental myopia, was associated with a greater risk of early-onset myopia in Asian, Hispanic, non-Hispanic white, and African American children. The observed associations of parental myopia in children as early as 1 year of age and in children without myopia suggests that genetic susceptibility may play a more important role in early-onset myopia and that parental myopia may contribute to myopia in children by setting up a more myopic baseline before school age.
About Ailsa
Ailsa Lane是一款位于英格兰肯特的隐形眼镜眼镜师。她目前正在通过荣誉完成她的先进文凭，并通过荣誉，在理解科学研究并发现其临床实践中的翻译，点燃了她的兴趣和技能。
