SightGlass Vision, a clinical-stage R&D company focused on myopia solutions, have released some early data from the CYPRESSclinical trial。The study is investigating a novel lens design, aiming to reduce myopia progression. This multi-site study includes 256 children across America and Canada, between -0.75 and -4.00DS from 6 to 10 years of age. They have tested two undisclosed lenses (which clinicaltrials.gov lists as “single vision lens”) against a control single vision lens, with the study planned to continue over 36 months, measuring refraction and axial length outcomes.
提到了一年的数据分析，该公司宣布“与对照镜头相比，两个测试臂的优越性”。这项研究具有非常严格的参数，不包括具有任何形式的先前近视控制的儿童，仅包括1.25DC的散光。明年的观光机承诺24个月的临时数据分析，因此请继续关注。
这对您的练习意味着什么？Nothing just yet, but an efficacious spectacle lens option for myopia control is an important potential development. Watch this space.
杰里米·古根海姆（Jeremy Guggenheim）和凯茜·威廉姆斯（Cathy Williams）写了一篇论文，讨论了有关基因检测的当前证据及其在预测高近视方面的功效。他们谈论的一篇论文Chen et alwhich looked at a cohort of Chinese twin children. In this paper, baseline refractive error was a strong predictor, however genetic information did not improve the accuracy when added to the calculator.
Guggenheim and Williams suggest that children whom are too young to have their myopia predicted from cycloplegic refraction may benefit from genetic testing, however current models are not accurate and need further work.
这对您的练习意味着什么？This is adding to the pool of information we have regarding genetics, causes and progression of myopia. Whilst this isn’t directly translatable to clinical process yet, in future, this may mean we can potentially advise parents and carers of at-risk children to modify their environmental risk factors, and even commence evidence based pre-myopia treatments.
尼古拉·洛根（Nicola Logan）和詹姆斯·沃尔夫索恩（James Wolffsohn。由于一些矛盾的结果和可变的研究质量，校正肯定没有受益，在某些研究中，肌病的进展增加了。两者兼而有经常作为全世界的科primary eye care providers和ophthalmologists。
The overall findings were that "there is no strong evidence of benefits from un-correction, monovision or over-correction. Hence, current clinical advice advocates for the full-correction of myopia. Further studies are warranted to determine the level of myopia that can be left uncorrected without impacting on myopia progression and how this changes with time."
This study resulted a subsequent给编辑的信which stated that the differences in the under-correction studies were small, and that "maintaining continuous full-correction of myopia is an ideal situation that is difficult to achieve in clinical practice." This does bring to mind that under-correction is frequently experienced by progressing myopes, even if unintentional.作者回答that the "current academic literature does not shed light on the effects of maintaining full correction of myopia between study visits.", but also that "more frequent appointments and optimisation of correction would be costly time-wise and financially."
这对您的练习意味着什么？这项系统的审查增加了支持放弃近视控制策略并完全纠正年轻肌关方的支持。随后对本文的回应还会想到，尽管我们尽了最大的努力，但我们年轻的进步近视可能会花费一定比例的时间。佩戴时间也会影响孩子在约会之间进行全面，不足或没有纠正的经历。
About Cassandra
Cassandra Hainesis a clinical optometrist, researcher and writer with a background in policy and advocacy from Adelaide, Australia. She has a keen interest in children's vision and myopia control.
